Large-scale proteomics identified SEMA6B, SFRP3, COMMD7, BMX, and VCAM1 as biomarkers highly associated with clinical portal hypertension in children with biliary atresia. The expression of the biomarkers in liver epithelial, endothelial, and immune cells support their potential role in the mechanisms that cause portal hypertension.
Study partnership will address disparities in hypertension control among racial and ethnic minority populations
Leader in broad-based finance and government contracting, Chauncey Lynch appointed to head Arbor Research finance team
Experienced business development professional Shanthy Edward, M.A., Psy.D. joins Arbor Research as Vice President of Strategic Growth & Chief Growth Officer.
Leaders in public health and social justice, Deborah Klein Walker, EdD, Med, BA and Gerald M. Croan, SB, MCP join Arbor Research’s Board of Directors
Seasoned business leader and researcher, Chris Spera, Ph.D, takes the helm at Arbor Research, succeeding retiring president, Robert M. Merion, M.D. FACS.
The Dialysis Outcomes and Practice Patterns (DOPPS) Program has expanded the DOPPS Practice Monitor (DPM) to include peritoneal dialysis (PD). The DPM-PD now reports the most up-to-date trends in care for patients receiving chronic PD in the US.
In a 1-year-old female patient with normal GGT cholestasis and bile duct paucity, we identified a homozygous truncating pathogenic variant (c.198delA, p.Gly67Alafs∗6) in the ABCC12 gene (NM_033226). Five additional rare ABCC12 variants, including a pathogenic one, were detected in our cohort.
Using data from the United States Renal Data System (USRDS), our researchers calculated access procedure (intervention) rates in the US for patients starting hemodialysis with an AVF or AVG created during their first year of hemodialysis therapy between July 1, 2012 and December 31, 2014 (N = 73,027).
Regional variation in glutathione metabolism underlies sensitivity to the biliary toxin biliatresone and may account for the reported association between BA transplant-free survival and glutathione metabolism gene expression.
