News and press

Arbor Research, LLC is pleased to announce the award of three domains on the GSA OASIS+ Total Small Business vehicle. Arbor Research is poised to offer solutions in the following areas: Management and Advisory Services: Providing agencies with specialized management and consulting services that improve efficiency, performance, and delivery of results. Technical and Engineering Solutions:

December 5, 2024 — Arbor Research Collaborative for Health is proud to announce an innovative collaboration with the Nephrology Associates of Northern Illinois and Indiana (NANI), the largest private nephrology practice in the United States. This partnership marks a significant milestone in advancing chronic kidney disease (CKD) research and management by leveraging NANI’s extensive patient-level

Arbor Research Collaborative for Health is excited to announce a partnership with CSL Vifor to launch a multinational registry designed to capture real-world outcomes of difelikefalin (Kapruvia®), a newly-approved treatment for chronic kidney disease-associated pruritus (CKD-aP) in hemodialysis (HD) patients. Known as PARADIGM (PAn european Registry Addressing pruritus in DIalysis with a focus on Goal

The Dialysis Outcomes and Practice Patterns Study (DOPPS) Program at Arbor Research Collaborative for Health is pleased to share their recent publication recognized as one of the most- downloaded articles at Kidney International Reports in the past few weeks titled “Alkaline Phosphatase and Parathyroid Hormone Levels: International Variation and Associations With Clinical Outcomes in the

Arbor Research Collaborative for Health (Arbor Research) recently welcomed Dr. Ping Yu, as Chief Growth Officer. In his new role at Arbor Research, Dr. Yu will lead the Strategic Growth Team (SGT) to further expand Arbor Research’s growth initiatives. Dr. Yu brings a wealth of experience in health data, analytics, research, and evaluation, with a

Christopher Spera, PhD, President & CEO of Arbor Research Collaborative for Health, has published “Facing Evidence Fears: From Compliance to Learning”, in the Brookings Publication titled “Next Generation Evidence”, which proposes a paradigm shift towards a learning framework to elevate the impact of health and social programs across the United States. Dr. Spera delves into

Deepika Laddu, PhD, a Senior Research Scientist at Arbor Research Collaborative for Health, has published exciting new research in Circulation concerning the health benefits of resistance training, particularly related to cardiovascular disease (CVD) risk factors. Dr. Laddu is coauthor on the paper, “Resistance Exercise Training in Individuals With and Without Cardiovascular Disease: 2023 Update: A

Arbor Research Collaborative for Health (Arbor Research) is pleased to announce its successful award of a position in a new subgroup within the General Services Administration (GSA) Schedule Contract focusing on Program Evaluation Services. The establishment of this subgroup will streamline the federal procurement process. Program evaluation is a crucial aspect of federal initiatives, providing

Individuals with BSEP deficiency with one p.E297G or p.D482G mutation and one PPTM have a similarly severe disease course and low responsiveness to siEHC as those with two PPTMs.

Featuring new scientific work with internationally-known speakers, expert panels, early career investigators, and audience participation.

The new office is located in the Metro DC area near clients and partners, offering convenience for meetings and collaboration.

Dr. Stanik to assist Arbor Research with further expansion into long-term care, behavioral health, and mixed methods research

Using a mouse model of BA and human liver gene expression data collected by ChiLDReN, we were able to confirm the likely activation of this pathway known as TWEAK/FN14 in association with liver fibrosis. We further showed that inhibition of this pathway pharmacologically was associated with near complete elimination of fibrosis in the mouse model of BA.

Arbor Research will support AHRQ in developing their patient centered outcomes research trust fund (PCORTF) strategic plan, logic model, and theory of change.

Dr. Roberto Pecoits-Filho will lead as the scientific and clinical leader of the world-renowned Dialysis Outcomes and Practice Patterns Study (DOPPS).

Arbor Research will work closely with the Centers for Disease Control and Prevention’s National Healthcare Safety Network to evaluate the ability of electronic health record (EHR) vendors to successfully implement and disseminate a standardized system for Clostridioides difficile infection (CDI) reporting into their EHR system, and assess the concordance of EHR versus manual-based reporting of CDIs by nursing homes.

Arbor Research will collaborate with prime contractor Lewin Group, as well as with the University of Michigan Kidney Epidemiology and Cost Center and ICF to assess the effectiveness of each model.

Large-scale proteomics identified SEMA6B, SFRP3, COMMD7, BMX, and VCAM1 as biomarkers highly associated with clinical portal hypertension in children with biliary atresia. The expression of the biomarkers in liver epithelial, endothelial, and immune cells support their potential role in the mechanisms that cause portal hypertension.

Study partnership will address disparities in hypertension control among racial and ethnic minority populations

Leader in broad-based finance and government contracting, Chauncey Lynch appointed to head Arbor Research finance team

Experienced business development professional Shanthy Edward, M.A., Psy.D. joins Arbor Research as Vice President of Strategic Growth & Chief Growth Officer.

Leaders in public health and social justice, Deborah Klein Walker, EdD, Med, BA and Gerald M. Croan, SB, MCP join Arbor Research’s Board of Directors

Seasoned business leader and researcher, Chris Spera, Ph.D, takes the helm at Arbor Research, succeeding retiring president, Robert M. Merion, M.D. FACS.

The Dialysis Outcomes and Practice Patterns (DOPPS) Program has expanded the DOPPS Practice Monitor (DPM) to include peritoneal dialysis (PD). The DPM-PD now reports the most up-to-date trends in care for patients receiving chronic PD in the US.

In a 1-year-old female patient with normal GGT cholestasis and bile duct paucity, we identified a homozygous truncating pathogenic variant (c.198delA, p.Gly67Alafs∗6) in the ABCC12 gene (NM_033226). Five additional rare ABCC12 variants, including a pathogenic one, were detected in our cohort.

Using data from the United States Renal Data System (USRDS), our researchers calculated access procedure (intervention) rates in the US for patients starting hemodialysis with an AVF or AVG created during their first year of hemodialysis therapy between July 1, 2012 and December 31, 2014 (N = 73,027).

Regional variation in glutathione metabolism underlies sensitivity to the biliary toxin biliatresone and may account for the reported association between BA transplant-free survival and glutathione metabolism gene expression.

Dr. Robert M. Merion, MD, FACS has announced that he will step down as President and Chief Executive Officer of Arbor Research Collaborative for Health by August 2021.

Our finding of de novo variants in genes linked to evolutionarily conserved stress responses (STIP1 and REV1) suggests that exploration of how genetic susceptibility and environmental exposure may interact to cause BA is warranted.

Our collaborator on the National Living Donor Assistance Center (NLDAC) project, Amit Mathur, MD, transplant surgeon at the Mayo Clinic of Arizona, has been selected to receive the prestigious 2020 Vanguard Award from the American Society of Transplant Surgeons (ASTS), in recognition of his recent publication in Clinical Transplantation, “Return on investment for financial assistance for living kidney donors in the United States.”

In studies of liver tissues from infants with cholestasis, we identified a 14-gene expression pattern that associated with transplant-free survival for 2 years.

How distress from itchy skin impacts patient health and quality of life

Generic medications reduce the lifetime costs of organ transplantation